SUMMARY

PART I
In part I of this thesis we investigated the effects of stress on hippocampal synaptic plasticity in both mice mand rats. The stressful situations used were: exposure of animals to acute (1 hour) or chronic stress (21 days) and in vitro exposure of hippocampal slices to elevated levels of corticosterone (20 minutes).

The following results were obtained:

Chapter 2

Chapter 3

PART II
In part II we investigated the effects of short term exposure to corticosterone and chronic stress on dendritic morphology and spine density of hippocampal CA1 neurons. Two different substrates of the hippocampal formation were used: organotypic slice cultures and acute slices.

The following results were obtained:

Chapter 4

Chapter 5