7. DEGENERATIVE DISEASES OF THE NERVOUS SYSTEM: FROM CLINIC TO BENCH

Aim
This is a 1-week course and will be organized every other year. The course aims to provide up-to-date in-depth information on different neurodegenerative diseases. This field is advancing rapidly; causal genes have been identified, animal models have been developed and novel diagnostic and therapeutic strategies are applied. The course will cover clinical aspects, genetics, diagnostics, molecular mechanisms, cellular and animal models and therapeutics.

Contents
Topics: Dementia (Alzheimer and vascular dementia), motor diseases (Parkinson, Huntington), white matter disease (MS, vanishing white matter), peripheral neuropathies.

Desired background level of participants
- The Molecular Biology of the Cell, 5th edition, Edited by Alberts et al. (Or similar chapters of earlier editions)
* Part I – Introduction to the Cell
* Part II – Basic genetic mechanisms
* Part IV – Internal organization of the cell

- Neuroscience, 5th Edition 2012, Edited by Purves et al. (Or similar chapters of earlier editions)
* Unit I - Neural Signalling – ch 2-8
* Unit III – ch 18: Modulation of Movement by the Basal Ganglia
* Unit IV – ch 25 Repair and regeneration of the Nervous system
* Unit V – ch 31 Memory

Difference between PhD- and master-course
Not applicable.

Duration of the course / ECTS
40 hrs / 1,4 ECTS

Format
Lectures and neuropathology practical

Maximum number of participants
n.a. (i.e. there is a maximum number of participants in the neuropathology practical)

Organizers
Prof.dr. S. Amor (VUmc)
Dr. W. Scheper (VUmc)

Year / dates next course
The next course will be organized in 2018.

Program of course
See downloadable file

Registration through
Els Borghols (els.borghols@vu.nl )